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Calcium Signalling: Intracellular calcium dynamics is highly organized in time and space. We focus on the molecular mechanisms responsible for this organization, which allows calcium to serve as a universal second messenger. Particular emphasis is put on the role of cellular calcium signalling in health...

The composition of microbial communities is dynamic: The relative abundances of species within a community vary with time and change with environmental conditions. We are developing mathematical and computational models to study the response of such microbial communities to environmental perturbations or to explain the...