The objectives of the projets are: (i) to establish the multi-omics cell type-specific profiles for pancreatic Langerhans islet cells to the pathogenesis of diabetes; (ii) to quantify the heterogeneity of cells in Langerhans islet samples; (iii) to determinate the effect methylation DNA age-acceleration in the pathogenesis of diabetes relative to chronological age.
Matthieu Defrance (PI, IB2), Miriam Cnop (PI, ULB Center for Diabetes Research), Decio Eizirik (PI, ULB Center for Diabetes Research), Anthony Piron (PhD Student).
IB2, ULB Center for Diabetes Research