Tools

Deogen

Deogen 2

DynaMine

DynaMine is a fast predictor of protein backbone dynamics using only sequence information as input.

DIDA

DIDA (DIgenic diseases DAtabase) is a database that provides detailed information on genes and associated genetic variants involved in digenic diseases, the simplest form of oligogenic inheritance.

Varcopp

Disomine

Prediction of protein disorder from sequence only.

Noumenon

Noumenon is a Contact Prediction validation dataset developed by G. Orlando, D. Raimondi and W. Vranken.

Sephiroth

Sephiroth is a disulfide connectivity pattern predictor based on evolutionary information retrieved from Multiple Sequence Alignments (MSAs). The algorithm has been designed by Gabriele Orlando, Daniele Raimondi and Wim Vranken.

PhyloCys

PhyloCys is a disulfide connectivity pattern predictor based on evolutionary information and phylogenetic trees inferred from Multiple Sequence Alignments (MSAs).

Xhresmoi

Investigating the molecular mechanisms behind uncharacterized cysteine losses from prediction of their oxidation state.

KeRF

Python implementation of the Random Forest Kernel.

WARP

WARP is an alignment-free tool for ultra-fast protein homology detection. It evaluates the similarity between two proteins by computing an approximate Dynamic Time Warping score on some compressed numeric representation of the target proteins. It then evaluates the likelihood of two proteins being homologous using a Random Forest classifier.

Rigapollo

Rigapollo is a pairwise alignment method based on a HMM-SVM.

Orval

Orval (Oligogenic Resource for Variant Analysis) provides a webplatform wherein the exome of a single patient can be analysed in terms of of the combinations of variants within genes, producing an oligogenic pathogenicity network that is annotated with biological and pathway information.