Interuniversity Institute of Bioinformatics in Brussels

(IB)2 is a collaborative bio-informatics research environment in Brussels.

The goal of the (IB)² is to bring together research groups in and around Brussels requiring bioinformatics and computational biology expertise. (IB)² is an interuniversity, cross-faculty (Medicine, Sciences, and Applied Sciences) collaborative space located on the La Plaine campus of the Université Libre de Bruxelles.

Our mission

Harness and scale bioinformatics expertise

Increasing the impact of bioinformatics research by bringing together experts from different fields to tackle various (bio) medical problems with the aim to advance fundamental research as well as assist clinicians in helping patients.

Provide infrastructure

Enable interdisciplinary and interuniversity research collaborations in bioinformatics by providing a physical location for research, meetings, collaborations, seminars as well as high-performance computer facilities, including the ULB-VUB computing center.

Reach scientific excellence

Allow Technology Transfer through training, education, innovation and collaborations. The (IB)² has the ambition to evolve into a competitive structure of scientific excellence, recognized at national and international level.

Our skills

The researchers at IB2 form a diverse cast of individuals coming from various scientific backgrounds. Together they offer numerous different skills and extensive knowledge covering a multitude of research domains.

Show skills

Machine Learning

Learning patterns from labelled and unlabelled data using classification, regression and clustering techniques.

Experts

Tom Lenaerts
Ann Nowé
Gianluca Bontempi
Charlotte Nachtegael
Sofia Papadimitriou
Nassim Versbraegen
Claudio Reggiani
Catharina Olsen
Alexandre Renaux
Simon Boutry

Structural Bioinformatics

Prediction and analysis of molecular level protein data.

Experts

Wim Vranken
Tom Lenaerts
Marianne Rooman
Anmol Gautam
Gabriele Orlando
Taushif Khan
François Ancien
Niloofar Shiranivadez
Ibrahim Tanyalçin

Genomics

Analysing the structure, function, evolution, and mapping of genomes.

Experts

Matthieu Defrance
Claudio Reggiani
Nicolas Dierckxsens
Ibrahim Tanyalçin
Guillaume Smits
Catharina Olsen
Tom Lenaerts
Charlotte Nachtegael
Sofia Papadimitriou
Alexandre Renaux
Nassim Versbraegen
Sonia Van Dooren
Didier Croes
Catheline Vilain
Youssef Bouysran
Julie Soblet
Stefan Weckx
Rudy Pelicaen

Epigenetics

DNA methylation, histone modification and gene expression.

Experts

Matthieu Defrance
Robin Grolaux
Madalina Ciortan
Anthony Piron

Evolutionary Dynamics

The study of evolving systems which involve competition and natural selection.

Experts

Tom Lenaerts
Nathaniel Mon Père
Sylvie Vande Velde
Patrick Mardulin
Jelena Grujić
Nicholas Dierckxsens

Oligogenic Diseases

The study of rare genetic disorders that require combinations of multiple mutated genes.

Experts

Tom Lenaerts
Sofia Papadimitriou
Charlotte Nachtegael
Nassim Versbraegen
Simon Boutry
Alexandre Renaux
Gillaume Smits
Catheline Vilain
Sonia Van Dooren

Pathogenicity Prediction and Ranking

Development of computational tools to predict the pathogenicity of genes and genetic mutations and to prioritise the most relevant pathogenic results

Experts

Sofia Papadimitriou
Nassim Versbraegen
Tom Lenaerts
Wim Vrancken
Marianne Rooman
Ibrahim Tanyalçin
Taushif Khan
François Ancien

Systems Biology

The computational and mathematical modeling of complex biological systems.

Experts

Tom Lenaerts
Sophie de Buyl
Stefan Vet
Nathaniel Mon Père
Sylvie Vande Velde
Catharina Olsen
Didier Gonze
Jelena Grujić
Lana Descheemaeker

Big Data Analysis

High-throughput analysis and manipulation of large datasets.

Experts

Charlotte Nachtegael
Sofia Papadimitriou
Nassim Versbraegen
Catharina Olsen
Tom Lenaerts
Gianluca Bontempi
Ann Nowé
Stefan Weckx
Matthieu Defrance
Catharina Olsen
Claudio Reggiani

Ongoing projects

206

publications

Publications per year

Since its creation in 2013, (IB)² has been making significant contributions to science.

See All Our projects

Recent Projects

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Bioinformatics Applications
Evolution and ecology
Genomics and Genetic Bioinformatics
Structural Bioinformatics
Systems Biology

Identifying the mechanisms involved in transducing binding information through SH3-SH2 supradomains and their role in regulating the activity of members of the family of Src kinases

Structural Bioinformatics

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(IB)2 provides monthly seminars with prominent speakers in the field to promote scientific collaboration and dissemination.

238

seminars and counting

Upcoming seminars

There are no upcoming events.

Our past seminars

IB2 Research Day 2023
6 October 2023 @ 9 h 30 min - 17 h 00 min
Journal Club – Charlotte Crauwels
16 June 2023 @ 12 h 00 min - 13 h 00 min
Journal Club – Emma Verkinderen
2 June 2023 @ 12 h 00 min - 13 h 00 min

View all

Latest publications

1. Chromosome-level genome assembly of the bay scallop Argopecten irradians

Scientific Data, December 2024 by Grouzdev D.

2. Correction to: Do fish gut microbiotas vary across spatial scales? A case study of Diplodus vulgaris in the Mediterranean Sea (Animal Microbiome, (2024), 6, 1, (32), 10.1186/s42523-024-00319-2)

Animal Microbiome, December 2024 by Lilli G.

Organisation

The Interuniversity Institute of Bioinformatics in Brussels is a new interdisciplinary research initiative supported by ULB and VUB universities hosted in the BC building of the ULB La Plaine Campus.