Open position for a Bioinformatician

The Human Genetics research group, IRIBHM, ULB, supervised by Dr Marc Abramowicz,
recruits a bioinformatician for analysis of genome-wide DNA analysis from patients with
suspected genetic diseases, for gene discovery.

Presently whole exome sequences (WES), progress to full genome sequences (WGS) in the
future. Our laboratory’s main interests are patients with primary microcephaly, or congenital
hydrocephalus, or spontaneous tolerance to renal graft, and other conditions where large
cohorts of patients have been/will be DNA analyzed.

New Project: Identifying the mechanisms involved in transducing binding information through SH3-SH2 supradomains and their role in regulating the activity of members of the family of Src kinases.

Communication is essential at all biological scales. Our cells have been rigged with communication systems that allow them to respond properly to environmental cues. These systems, or signaling pathways, are composed of different proteins, whose activity is regulated by other proteins. This intricate regulatory system ensures that cells provide the right response, both in kind and magnitude. Errors in regulation often result in diseases.