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February 2019

Seminar Karoline Faust (KUL) : Emergent behaviour in a synthetic gut community

February 8 @ 15 h 00 min - 16 h 00 min
Forum F, ULB

Due to its complexity and the impact of the human host, it is hard to obtain a mechanistic understanding of the gut microbial community from sequencing data alone. Synthetic communities are an excellent tool to complement in vivo studies. Their dynamics can be accurately monitored…

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Seminar Genevière Dupont (ULB) – Intracellular calcium dynamics: from modeling to physiology

February 15 @ 15 h 00 min - 16 h 00 min
Forum F, ULB
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Seminar Rob Jelier (KUL) : Simulating Cellular Movements in Early C. elegans Embryogenesis

February 22 @ 15 h 00 min - 16 h 00 min
Forum F, ULB

Abstract: Understanding how cells position themselves correctly in multicellular environments is a fundamental challenge in developmental biology. We use the invariable embryogenesis of C. elegans and a modelling approach to better understand the underlying mechanisms driving cellular movements. We developed a simulator to model the…

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March 2019

Journal Club: Charlotte

March 8 @ 15 h 00 min - 16 h 00 min
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Seminar Zeynep Kalender Atak, Heterogeneity of melanoma genomes and cell states (KUL)

March 15 @ 15 h 00 min - 16 h 00 min
Forum F, ULB

Heterogeneity in cancer is a consequence of both irreversible genetic changes and reversible transcriptional changes. Melanoma is prime example for this since on the genomic level melanomas have a high mutational burden leading to inter and intra-tumor heterogeneity while on the transcriptomic level they can…

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Journal Club: Nathaniel and Rudy – “Cell movement, chemotaxis, and statistical physics”

March 22 @ 15 h 00 min - 16 h 00 min
(IB)^2 common room
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April 2019

Journal Club: Sofia

April 5 @ 15 h 00 min - 16 h 00 min
(IB)^2 common room

In the era of the rise against statistical significance: what have we (not) learnt from millions of scientific papers with P-values

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May 2019

Seminar Thierry Mora (ENS, Paris) – Diversity and response in immune repertoires

May 3 @ 15 h 00 min - 16 h 00 min
Solvay Room (ULB, NO building 5th floor)

The diversity of repertoires of B-cell and T-cell receptors is generated by a stochastic process of gene rearrangement called VDJ recombination, and is later sculpted by selection, clonal proliferation, and somatic hypermutations. I will show how these processes can be learned quantitatively from high-throughput repertoire…

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Journal Club: Alex – Knowledge representations for contextualising disease associated molecular signatures

May 10 @ 15 h 00 min - 16 h 00 min
(IB)^2 common room
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Journal Club – Simon

May 17 @ 8 h 00 min - 17 h 00 min
(IB)^2 common room

pBRIT: gene prioritization by correlating functional and phenotypic annotations through integrative data fusion.

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